A Clinical Study of prevalence of Hepatitis B Virus , Hepatitis C Virus and Syphilis ( T . Pallidum ) in HIV positive patients

To study the prevalence of Hepatitis B Virus infection, Hepatitis C Virus infection and Syphilis (T. Pallidum) in HIV positive patients. This crosssectional study was conducted on 332 HIV positive patients who presented to Dr. Baba Saheb Ambedkar Hospital ,Rohini, New Delhi from December2007 to March 2010 .The prevalence of Hepatitis B, Hepatitis C and and Syphilis in HIV positive patients in aged >15 years and their correlation with regard to history , clinical examination and laboratory parameters were studied.In our study group most of the patients were infected with HIV alone (300/332) 90.36% and the number of HIV with co-infected patients were small but significant 32/332(9.64%). The prevalence of HIV –HBV co-infection was 9/332 (2.71%), HIV –HCV co-infection was 4/332 (1.21%), HIVSyphilis co-infection was 17/332 (5.12%) and HIV-HBV-HCV Co-infection 2/332(0.60%).The present study shows that the HIV patients may be co-infected with other infectious diseases which have mode of transmission through sexual, blood and blood products, materno-fetal route and others, thus patient may be co infected with HBV, HCV and syphilis through these common modes of transmission. The presence of such co-infection may not only affect the natural course of HIV but may also influence the clinical presentation, therapeutic response and the course of other infection also.